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Conduct a literature review report (1000-1200 words) on the disease below:1. Phenylketonuria
Requirements and Guidelines:• Your review report should:1- be written in your own words, 2-including in text-citation, andaddressing ALL of the following sections:o Molecular basis of the disease: Recognize the mutation at the DNA level and how it leadsto protein malfunction that can lead to the disease.o Diagnostic methods: Explain in your own words two molecular methods used to identifythe disease. At least one method should be nucleic acid diagnostic method. You shouldinclude here the extraction method for the nucleic acids used in this essay.o References: Include the articles discussed in your paper with MLA citation style.• Your paper should be in essay style, 1000-1200 words, double-spaced, Font 12 Arial.• Write in your own words (Plagiarism will not be tolerated!). Copying text in quotation marks isnot acceptable! You need to paraphrase in your own words.• Whenever referring to an article, citation should be included in-text.• The references should contain at least four journal research articles• Some suggestion for helpful resources to be used: EBSCO (access through AURAK Library), GoogleScholar (or any similar resource), PubMed, etc.• Include the following on the first page for this assignment
Criteria and Qualities:
Molecular basis of thedisease:
Student clearly recognised themutation at the DNA level andhow it leads to proteinmalfunction.
Diagnostic methods:Student did not explainthe molecular methodsused to identify thedisease with no focus ondetails:Student explained clearly bothmethods used to identify thedisease with great focus ondetails. At least one of themethods is nucleic aciddiagnostic method. Thestudent clearly describednucleic acid isolation methodin this essay.
The appropriate content inconsideration is covered indepth without beingredundant. Sources are citedwhen specific statements aremade.
Clarity of writing andwriting technique:
Writing is crisp, clear, andconcise. The writerincorporates the active voicewhen appropriate andsupports ideas with examples.No spelling, grammar, orpunctuation errors are made.
Citations/References:Proper MLA format:
Citation for the article didfollow MLA format. Essentialinformation was accurate andcomplete. At least fourreferences are journalresearch articles.
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