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Renal dosage adjustments based on est CrCI as calculated by CockcrofUgault equation, vs estGFR as calculated by MDRD? There are some merits to each one, especially since there are unknowns that need to be corrected for with each (which weight to use, how do you assign IBW for pts < 60in, how to account for changes in renal1. What is the current knowledge of the topic? 2. What recent work has been done in this field? 3. How can the literature you found be used to construct a coherent argument on this topic? 4. Is your argument clear and supported by current research/evidence? How strongly does this evidence refute past or current conflicting evidence? 5. What are other schools of thought/perspectives on this topic? Why do some opinions/ideas hold more weight than others? 6. In short, we want you to fully reason through your final assertion.
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